NanoString Blog
Category: nCounter
nCounter
Why Oligonucleotides Are Critical Components of DNA and RNA Expression Research
With all the advances in molecular biology over the last several decades, one of the most consistently used tools is the oligonucleotide. Oligonucleotides are relatively short (oligo) single-stranded sequences of…
nCounter
How DNA Barcoding Improves Gene Expression Analysis and Biomarker Discovery
The phrase “DNA barcoding” can be applied to several methods of using unique DNA sequences for identification purposes. Sometimes known as “molecular barcoding,” DNA barcoding describes the use of unique…
nCounter
How Cell Counters and Cell Type Profiling Can Help Analyze Gene Expression Profiles
Cell counters, also known as cell sorters, are instruments that separate and count specific cells of interest using characteristic properties of those cells. The original cell counters, known as Coulter…
Clinical Research nCounter
Gene Expression Can Drive Your Research to New Heights
The word “gene” refers not only to the actual physical DNA that codes the gene itself, but also to all related downstream events, including gene expression, gene regulation, and gene…
Data Security nCounter
Is your Lab Secure? Exploring the New Cyberbiosecurity World
As someone who is involved in molecular biology research, how often do you think about cybersecurity? Occasionally? Never? Perhaps you only think about them when you receive an email from…
Infectious Disease nCounter
An nCounter® in The Gambia: An interview with Tuberculosis Researcher Jayne Sutherland
NSTG: Jayne, it’s so lovely to meet you. Could you tell us about your background and your research interests? Jayne Sutherland: I’m an immunologist by training; for my Ph.D., I studied cancer.…
nCounter
Gene Expression Profiling Made Easy: The Birth of nCounter®
Nanostring: noun; a piece of DNA (probe) attached to a linear sequence of fluorophores made up of four different colors (barcode). Each probe is complementary to a unique target oligonucleotide.…
Digital Spatial Profiling GeoMx DSP nCounter Oncology Spatial Transcriptomics
New approaches to CAR-T therapy
What is CAR-T cell therapy? In the fight against cancer, immunotherapies that enlist and strengthen the power of a patient’s immune system to attack tumor cells have revolutionized treatment paradigms.…
Digital Spatial Profiling nCounter Neuroscience Spatial Transcriptomics
Neurodegenerative disorders and Parkinson’s disease.
The idiom “to lose one’s nerves” is literally true when it comes to neurodegenerative disorders. These disorders are characterized by the progressive loss of disease-specific neural populations in the brain…
nCounter Neuroscience Spatial Transcriptomics
Alzheimer’s Disease Pathology: Fear, Confusion, and the Search for a Cure
Alzheimer’s disease pathology: a short sentence loaded with fear, confusion, and incredulity. The word “Alzheimer’s” first appeared in a German psychiatry handbook called “General Psychiatry” on July 15, 1910. This…
Grants nCounter Q&A
NanoString People of Color and Allies (nPOCA) ERG Grant Support Program
2020 will be remembered as the year that a novel viral pandemic and the protests galvanized by the death of George Floyd disrupted modern society. These events, while seemingly unrelated,…
Immunology Infectious Disease nCounter
How NanoString nCounter® helps vaccine research: Part 2, A tale of three viruses
In the first part of this two-part blog series, I discussed NanoString nCounter® technology. nCounter allows biologists to quantify gene expression using a series of molecular probes. One application of…