NanoString Blog

Category: nCounter

Green DNA illustration


Why Oligonucleotides Are Critical Components of DNA and RNA Expression Research

With all the advances in molecular biology over the last several decades, one of the most consistently used tools is the oligonucleotide. Oligonucleotides are relatively short (oligo) single-stranded sequences of…

NanoString / March 3, 2023
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How DNA Barcoding Improves Gene Expression Analysis and Biomarker Discovery

The phrase “DNA barcoding” can be applied to several methods of using unique DNA sequences for identification purposes. Sometimes known as “molecular barcoding,” DNA barcoding describes the use of unique…

NanoString / March 2, 2023
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How Cell Counters and Cell Type Profiling Can Help Analyze Gene Expression Profiles

Cell counters, also known as cell sorters, are instruments that separate and count specific cells of interest using characteristic properties of those cells. The original cell counters, known as Coulter…

NanoString / March 1, 2023

Clinical Research nCounter

Gene Expression Can Drive Your Research to New Heights

The word “gene” refers not only to the actual physical DNA that codes the gene itself, but also to all related downstream events, including gene expression, gene regulation, and gene…

NanoString / March 1, 2023

Data Security nCounter

Is your Lab Secure?  Exploring the New Cyberbiosecurity World

As someone who is involved in molecular biology research, how often do you think about cybersecurity? Occasionally? Never? Perhaps you only think about them when you receive an email from…

Geoffrey Hummelke / May 30, 2022

Infectious Disease nCounter

An nCounter® in The Gambia: An interview with Tuberculosis Researcher Jayne Sutherland

NSTG: Jayne, it’s so lovely to meet you. Could you tell us about your background and your research interests? Jayne Sutherland: I’m an immunologist by training; for my Ph.D., I studied cancer.…

Elizabeth Schneider / March 24, 2022
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Gene Expression Profiling Made Easy: The Birth of nCounter®

Nanostring: noun; a piece of DNA (probe) attached to a linear sequence of fluorophores made up of four different colors (barcode). Each probe is complementary to a unique target oligonucleotide.…

Laura Tabellini Pierre / January 31, 2022
Rendering of oncology proteins

Digital Spatial Profiling GeoMx DSP nCounter Oncology Spatial Transcriptomics

New approaches to CAR-T therapy

What is CAR-T cell therapy? In the fight against cancer, immunotherapies that enlist and strengthen the power of a patient’s immune system to attack tumor cells have revolutionized treatment paradigms.…

Nirupama Deshpande / January 18, 2022
3d model of a neuron

Digital Spatial Profiling nCounter Neuroscience Spatial Transcriptomics

Neurodegenerative disorders and Parkinson’s disease.

The idiom “to lose one’s nerves” is literally true when it comes to neurodegenerative disorders. These disorders are characterized by the progressive loss of disease-specific neural populations in the brain…

Nirupama Deshpande / December 6, 2021

nCounter Neuroscience Spatial Transcriptomics

Alzheimer’s Disease Pathology: Fear, Confusion, and the Search for a Cure

Alzheimer’s disease pathology: a short sentence loaded with fear, confusion, and incredulity. The word “Alzheimer’s” first appeared in a German psychiatry handbook called “General Psychiatry” on July 15, 1910. This…

Nirupama Deshpande / November 22, 2021

Grants nCounter Q&A

NanoString People of Color and Allies (nPOCA) ERG Grant Support Program

2020 will be remembered as the year that a novel viral pandemic and the protests galvanized by the death of George Floyd disrupted modern society. These events, while seemingly unrelated,…

Trena Cormier / October 24, 2021

Immunology Infectious Disease nCounter

How NanoString nCounter® helps vaccine research: Part 2, A tale of three viruses

In the first part of this two-part blog series, I discussed NanoString nCounter® technology. nCounter allows biologists to quantify gene expression using a series of molecular probes. One application of…

Melanie Peffer / October 5, 2021