NanoString Blog
Digital Spatial Profiling
Spatial Profiling using the GeoMx RNA Assay for NGS Readout: Robust Technology for Identification of Novel Biomarkers and Early Detection of Melanoma
Early diagnosis of melanoma is critical for improved clinical outcomes and survival of patients. Yet disagreement in traditional histology-based diagnosis frequently occurs. Despite currently available molecular technologies, melanomas characterized by…
Oncology
A Transcriptomic Solution Customized for Your Every Need
The flexibility of the NanoString nCounter® platform has been designed to accommodate a wide range of organisms, molecular targets, and sample inputs. Researchers can request “made-to-order” Custom CodeSets for up…
Digital Spatial Profiling Miscellaneous Oncology
Meet NanoString Scientists at the AMP 2019 Annual Meeting & Expo
When Elaine Lyon, Ph.D., a scientist on the board of the Association for Molecular Pathology (AMP) was asked why she is involved with AMP, its activities and initiatives, she quoted…
Oncology
Top Challenges of Biofluid Samples when Profiling FFPE miRNA Biomarkers
In 1993, Dr. Victor Ambros’ lab discovered a small RNA sequence, Lin-4, that was “essential for the normal temporal control of diverse postembryonic developmental events in C. Elegans”. Sequence analysis…
Oncology
The bench side of organ transplant: Challenges and solutions
“It is infinitely better to transplant a heart than bury it to be devoured by worms,” said Dr. Christiaan Barnard, the father of the heart transplant. It’s hard to disagree…
Digital Spatial Profiling Miscellaneous
A day (or two) with the Experts: the 2019 EU NanoString Summits Crosstalk
Since 2017 NanoString has hosted day-long summits in some of the liveliest and most charming European locations, where scientists and key opinion leaders have had the opportunity to share with…
Oncology
Aiming at the Achilles’ heel of cancer: multiplexed lung cancer fusion detection without FISH or NGS
Lung cancer is the most commonly diagnosed cancer worldwide, and the leading cause of cancer deaths in the United States. It is generally divided into two types, non-small cell lung…
Autoimmunity Immunology
How to Resolve the Complexity of Autoimmune Diseases
What are Autoimmune Diseases? Autoimmune diseases are chronic inflammatory conditions, life-long debilitating illnesses with increased mortality, and high healthcare costs for therapy and care. They are systemic conditions characterized by…
Digital Spatial Profiling GeoMx DSP Spatial Biology Spatial Transcriptomics
GeoMx® DSP: What Surprised This Early Adopter Most
During her post doc years, Trieu My Van explored the effects of immuno check point blockade in melanoma patients, comparing samples from metastatic uveal and cutaneous melanoma tissues at the…
Neuroscience
A Strategic Attack Against Neurological Diseases
Neurological diseases are often multifactorial, brought on by a genetic and environmental tug-of-war and resulting in multifaceted clinical presentations. Such etiological complexity has hindered treatment progress and has necessitated well-thought-out…
Clinical Research Digital Spatial Profiling GeoMx DSP Spatial Biology Spatial Transcriptomics
How the Field of Immuno-Oncology is Changing Fast
Immuno-oncology, also known as cancer immunotherapy, is a treatment that harnesses the power of our immune system to fight cancer. The selective efficacy of immunotherapies continues to provide impetus for…
Autoimmunity
Q&A with Dr. Maureen McGargill, PhD: The Immune System’s Fine Line Between Health and Harm
Dr. McGargill earned her PhD at the University of Minnesota in Dr. Kristin Hogquist’s lab. There she studied T cell development, focusing on how autoreactive T cells are deleted during…