NanoString Blog
Spatial Transcriptomics
An Integrated Omics Approach: The Human Protein Atlas
Although humans have been using atlases for thousands of years, the word atlas was first coined in 1595 by the Flemish map maker Gerardus Mercator. In geographical terms, an atlas…
Spatial Transcriptomics
What is the human protein atlas used for?
In order to understand the role of each protein in various biological processes such as cell organization, signaling pathways, or disease mechanisms, it becomes essential to study protein expression with…
Digital Spatial Profiling
What is digital spatial profiling?
The function of biological systems depends on the spatial organization of their cells. Over the past decade, innovative technologies have emerged that can spatially localize and quantify gene expression of…
GeoMx DSP
Immunofluorescence Staining: An Overview
Immunofluorescence staining is an incredibly powerful yet simple imaging technique that optically detects the localization, distribution, and abundance of proteins at a cellular and intracellular level using fluorescent tags on…
GeoMx DSP
Digital Spatial Profiling
Understanding how gene expression orchestrates cellular organization within tissues is essential to gain mechanistic insights into development and disease. Spatial transcriptomics allows capturing of transcriptional activity along with positional context…
Digital Spatial Profiling GeoMx DSP Spatial Transcriptomics
FFPE Genomics: a Portal Into the World of Transcriptomic Research?
The emergence of spatial transcriptomics, with its ability to generate highly detailed maps of gene expression with spatial context, is revolutionizing biomedical research, particularly in developmental biology, cancer, immunology, and…
CosMx SMI
What are some examples of cell signals?
Cell signaling is one of my absolute favorite topics in molecular biology. In fact, a lecture on cell signaling during my sophomore year of college was the reason why I…
CosMx SMI
What are some examples of cell to cell interactions?
The coordination of 37.2 trillion cells is required for our bodies to function, but it can be difficult enough to coordinate a classroom of thirty students. How then are so…
CosMx SMI
Common questions in molecular biology: What is the importance of cell interactions?
Can you imagine if a cell could send an email? Or put in a work request? Think of it: Dear Immune System, I am infected by a virus. Please send…
CosMx SMI
Common questions in molecular biology: What are types of cell-cell interactions?
Much like bees or ants, cells are inherently social. Also like various hive-based insects, the social nature of the interactions are important for dictating function and well being of the…
CosMx SMI
Common questions in molecular biology: Why do we need biomarkers?
What does it mean to be healthy? If you go in for a regular wellness appointment at the doctor’s office, how does the doctor assess if you are healthy? Wellness…
CosMx SMI
Common questions in molecular biology: What can biomarkers tell us?
As we go about our day, we are surrounded by indicators. Our clocks tell us the time. Ovens will reveal their current temperatures and alert us when they’ve reached their…