NanoString Blog
nCounter
Why Oligonucleotides Are Critical Components of DNA and RNA Expression Research
With all the advances in molecular biology over the last several decades, one of the most consistently used tools is the oligonucleotide. Oligonucleotides are relatively short (oligo) single-stranded sequences of…
nCounter
How DNA Barcoding Improves Gene Expression Analysis and Biomarker Discovery
The phrase “DNA barcoding” can be applied to several methods of using unique DNA sequences for identification purposes. Sometimes known as “molecular barcoding,” DNA barcoding describes the use of unique…
nCounter
How Cell Counters and Cell Type Profiling Can Help Analyze Gene Expression Profiles
Cell counters, also known as cell sorters, are instruments that separate and count specific cells of interest using characteristic properties of those cells. The original cell counters, known as Coulter…
Clinical Research nCounter
Gene Expression Can Drive Your Research to New Heights
The word “gene” refers not only to the actual physical DNA that codes the gene itself, but also to all related downstream events, including gene expression, gene regulation, and gene…
Digital Spatial Profiling GeoMx DSP
The Birth of Spatial Genomics
NanoString catalyzed the spatial biology revolution in 2019 with the launch of the GeoMx® Digital Spatial Profiler (DSP), but did you know that the beginnings of this nascent field go…
CosMx SMI Spatial Biology Spatial Transcriptomics
What’s New at NanoString for 2023: The Arrival of the First Fully Integrated Single-Cell Spatial Solution
One of the interesting hallmarks of celebrating the start of a new year is the consumption of special foods. For example, in the American South Hoppin’ John, or black-eyed peas,…
Multiomics Spatial Analysis Spatial Transcriptomics
Integrated Spatial Multiomics Deconvolve Multicellular Dynamics in Pancreatic Cancer
In an extraordinary team effort led by the Center for Systems Biology at Harvard Medical School, in collaboration with NanoString, scientist Will Hwang and colleagues used integrated spatial multiomic and…
Digital Spatial Profiling Multiomics Spatial Analysis Spatial Transcriptomics
Spatial Multiomics Identifies New Actionable Therapeutic Targets
Pancreatic cancer represents 3% of the overall cancers in America and yet is responsible for 7% of all cancer deaths. The five-year relative survival rate – the cancer-related death rate…
CosMx SMI Spatial Molecular Imaging Spatial Transcriptomics
Spatial Multiomics Single-Cell Imaging Platform to Explore FFPE Tissues with Spatial Context
What is Spatial Multiomics? Spatial multiomics describe the ability to locate and quantify DNA, RNA, and protein in the three-dimensional space of a tissue. Decades of research have built a…
Multiomics Spatial Analysis Spatial Informatics
Spotlight on Spatial Informatics: Overlay of Structurally Profiled ROIs on Tissue Images with SpatialOmicsOverlay R Package
Spatial biology is changing the way we view biology. Advancements in spatial biology are now enabling us to compartmentalize a tissue in terms of cells, tissue structure, or disease state.…
Multiomics Spatial Analysis
Spatial Transcriptomics at the Single-Cell Level
Is spatial transcriptomics single-cell resolution? Yes. Recent advances in the field of spatial transcriptomics have made it possible to visualize RNA transcripts at the resolution of a single-cell and, in…
Miscellaneous
Meet our Outstanding Colleagues: Amanda
We call ourselves NanoStringers, and we bleed green! We proudly believe in the science and technology we make here. Meet us. You will love us! Amanda Ph.D., Field Applications Scientist,…